Female Smokers Are at Greater Risk of Airflow Obstruction Than Male Smokers. UK Biobank

Female Smokers Are at Greater Risk of Airflow Obstruction Than Male Smokers. UK Biobank.

RATIONALE The prevalence of chronic obstructive pulmonary disease (COPD) is increasing faster among women than among men. OBJECTIVES To examine sex differences in the risk of airflow obstruction (a COPD hallmark) in relation to smoking history. METHODS We analyzed 149,075 women and 100,252 men taking part in the UK Biobank who had provided spirometry measurements and information on smoking....

Prevalence of airflow obstruction in smokers and never-smokers in Switzerland.

The aim of the present study was to measure age-specific prevalence of airflow obstruction in Switzerland in smokers and never-smokers using pulmonary function tests and respiratory symptoms from 6,126 subjects participating in the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults. The lower limit of normal of the forced expiratory volume in 1 s/forced vital capacity ratio was use...

Higher Risk of Wheeze in Female than Male Smokers. Results from the Swedish GA2LEN Study

BACKGROUND Women who smoke have higher risk of lung function impairment, COPD and lung cancer than smoking men. An influence of sex hormones has been demonstrated, but the mechanisms are unclear and the associations often subject to confounding. This was a study of wheeze in relation to smoking and sex with adjustment for important confounders. METHODS In 2008 the Global Allergy and Asthma Eu...

Sex differences in emphysema phenotype in smokers without airflow obstruction.

Data on sex differences in emphysema are limited to chronic obstructive pulmonary disease. We aimed to verify whether such differences also exist in smokers without airflow obstruction, weighting their influence on the relationship between emphysema and clinical features. We evaluated both clinical and multidetector computed tomography (MDCT) data of 1,011 heavy smokers recruited by a lung canc...

Identifying smokers at risk for developing airway obstruction.